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The International Journal of the Royal Society of Thailand
Volume XI - 2019

Figure 5 Mosquito-cidal effects of ivermectin, across all drug regimens, stratified by Anopheles
dirus (a) and Anopheles minimus (b). Filled symbols represent the cumulative mean mosquito
mortality at 10 days post-blood meal, across the different ivermectin-containing drug regimens,
at each blood collection time point. Bars represent the 95% confidence intervals around these
means. DHA-PQP = dihydroartemisinin-piperaquine (Kobylinski et al, 2019).

RTS,S/AS01 vaccine study
RTS,S is the most advanced malaria vaccine and provides 30%-40%

protection for up to one year. The vaccine has been evaluated in over 15,000 mostly
African recipients and was developed for use in the expanded programme on
immunization for African children (von Seidlein et al, 2017). Malaria protection
from MDA will only be protective for one month while the malaria transmission
season in Thailand is up to six months. Even after successful MDA, residents
remain at risk for imported infections. Combining MDA with mass vaccinations
campaigns has the potential to interrupt falciparum malaria transmission
permanently. The Faculty of Tropical Medicine has innovated the use of RTS,S

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