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The International Journal of the Royal Society of Thailand
Volume XI - 2019

For pharmacogenomics to predict drug response, there is several
Pharmacogenomics tests available for assisted in selection the drug with higher
responsiveness. For examples, the CYP2C19 genotyping for selection of

clopidogrel, the IL28 genotyping to select interferon alpha. These tests help
saving costs, by not giving the drug to those who unlikely to response to the
drug. Recently, genotyping of NAT2 for adjusting the dosage of Isoniazid is likely
to be a cost-effective approach to use isoniazid.

The service pillar in the NCP Genomics Thailand

The service is in the plan is referred to the national service for genomic
medicine. To implement the national level clinical or public health services based
on the new technology, sustainability is the most important in the design of the
service. The human resource development and technology transfer plan is vital
for sustainability of this implementation. The health insurance organizations or
the payers, would need to acquire the capability and understanding of the benefit
and risk of genomic medicine. The provider would need the reskill and continuous
professional development (CPD) to update the knowledge for the current
workforce. Preparation for the health care service providers, payers and the
general public are the key to generalization of the genomic medicine approach.
The Ministry of Public Health (MOPH) is the principle organization for
implementation of this NCP Genomics Thailand (GeTH) based on the cabinet
approval on 26th March 2019, with Health System Research Institute (HSRI),
as secretariat. It is imperative for the MOPH and National Health Security

Office (NHSO) to collaborate with all organizations both public and privates to
realize the benefit of genomic medicine for Thai population. Sustainability can be
achieved when the universal health coverage integrated the genomic medicine
into their program preparation principles, appropriate use of the genomic
medicine would solve the intractable health problems in Thailand.

Surakameth Mahasirimongkol
Sacarin Bunbanjerdsuk 97

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