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The International Journal of the Royal Society of Thailand
                                                                                                Volume XV-2023




                     pandemic. To ensure these studies were uninterrupted, after initial discussions
                     among all partners efforts were made to continue research with precautionary

                     adaptations to activities determined by the pandemic situation as it evolved over
                     time. Community-based studies were implemented without mass gatherings
                     and so engagement strategies were adapted to avoid the risk to participants of
                     high-risk exposure events. Clinical trials continued to recruit patients where

                     personal protective gear was available. High COVID-19 vaccination coverage in
                     Cambodia also offered early relaxations of government-imposed restrictions
                     which allowed to continue the ongoing research. During travel restrictions
                     novel  monitoring  and  supervision  strategies  were  necessary  and  remote

                     monitoring and teleconferencing was introduced. In some studies, serious delays
                     to supplies were experienced and patient recruitment was curtailed but this
                     occurred within acceptable limits. Building on the pre-established collaborations
                     with the national and international partners, MORU’s field sites adapted and

                     utilized the flexible approaches to continue the ongoing studies. Although delays
                     and difficulties due to COVID-19 restrictions affected some aspects of our research,
                     strong collaboration, trust among the partners, and adaptations facilitated the
                     successful completion of the studies.




                  Keywords: health research; collaboration; COVID-19 pandemic; multi-stakeholder

                  engagement





                  Introduction

                         Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory
                  syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Decem-

                  ber 2019 in Wuhan, China and from there the outbreak then rapidly spread interna-
                  tionally (Sharma et al, 2020). The Emergency Committee of the World Health Organi-
                  zation declared a Public Health Emergency of International Concern (PHEIC) on the
                  30  of January 2020 (WHO, 2020). Thereafter, the pandemic itself, and the drastic
                     th
                  measures taken in response to limit COVID-19 transmission, caused immediate and
                  unprecedented difficulties to all counties in early 2020. The medical and public health
                  systems and medical research have been severely impacted upon during 2020-22
                  (Moynihan et al, 2021). During the first years of the pandemic, implementing research

                  in Southeast Asia was affected by border closures and travel restrictions, the redirection




                        Dysoley Lek et al.                                                                35
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