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The International Journal of the Royal Society of Thailand
              Volume XI - 2019



              Conclusion

                      The development of next-generation sequencing has greatly enriched our
              knowledge of the precise genetic alterations of human diseases during the past
              decade. Precise molecular diagnosis will enable targeted therapies and better

              management. Efforts are underway to incorporate patient phenotype and genotype
              data to develop databased predictors of treatment response as well as potential
              novel therapeutics. Genome editing and induced pluripotent stem cell technologies
              could accelerate the path to precision medicine. Advances in genomics and
              precision health are creating new opportunities for evidence-based and patient-
              centered care achieving the goal of improving clinical outcomes and promoting
              patients’ quality of life.


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              84                                     Precision Medicine in Hereditary Neurological Disorders:
                                                                         From Diagnosis to Treatment



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