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«“√ “√ √“™∫— ≥±‘µ¬ ∂“π ªï ∑’Ë Ú˜ ©∫— ∫∑’Ë Û °.§.-°.¬. ÚıÙı π‘ æπ∏å æ«ß«√‘ π∑√å ¯ıı ®“°π“¬·æ∑¬å Allan B. Scott „π √“§“‡æ’ ¬ß Ù ‡À√’ ¬≠ À√— ∞ µà Õ Ò Àπà «¬ À√◊ Õµà Õ Ò ¢«¥. „πªí ®®ÿ ∫— π √“§“¬“‰¥â ‡æ‘ Ë ¡‡ªì π Û ‡À√’ ¬≠ À√— ∞ µà Õ Ò Àπà «¬ À≈— ß®“°∑“ß ¡À“«‘ ∑¬“≈— ¬ ´“πø√“π´‘ ‚° ¢“¬ ≈‘ ¢ ‘ ∑∏‘Ï ¬“π’È „Àâ °— ∫∫√‘ …— ∑ Allergan ·Àà ߪ√–‡∑» À√— ∞Õ‡¡√‘ °“. „πªí ®®ÿ ∫— π¡’ ‡æ’ ¬ß Ù ª√–‡∑»„π ‚≈°‡∑à “π—È π∑’Ë “¡“√∂º≈‘ µ “√™’ «¿“æ π’È ‰¥â §◊ Õ ª√–‡∑» À√— ∞Õ‡¡√‘ °“ ´÷Ë ß„™â ™◊Ë Õ«à “ çBotoxé, ª√–‡∑»Õ— ß°ƒ…„™â ™◊Ë Õ«à “ çDysporté, ª√–‡∑»≠’Ë ªÿÉ π„™â ™◊Ë Õ«à “ çJapanese Botoxé ·≈– ª√–‡∑»®’ π. ªí ®®ÿ ∫— π Japanese Botox ‰¥â ‡≈‘ °º≈‘ µ‰ª·≈â «. ”À√— ∫ª√–‡∑» ‰∑¬‡√“¬— ߉¡à ¡’ »— °¬¿“æ‡æ’ ¬ßæÕ„π °“√∑’Ë ®–º≈‘ µ “√‡§¡’ ™’ «¿“æπ’È ¢÷È π‡Õß ‡π◊Ë Õß®“°µâ Õß≈ß∑ÿ π Ÿ ß¡“° ·≈–„π °“√·¬° “√π’ È ÕÕ°¡“π—È π„π¢≥–π’È ª√–‡∑»‰∑¬¬— ߉¡à ¡’ ‡™◊ È Õ §≈Õ µ√‘ ‡¥’ ¬¡ ‡°Á ∫Õ¬Ÿà „πÀâ Õߪؑ ∫— µ‘ °“√¢Õß ∂“∫— π „¥‡≈¬ ·≈–ß∫ª√–¡“≥„π°“√º≈‘ µ ·≈– √â “ß‚√ßß“π·¬° “√‚∫∑Ÿ ≈‘ π— ¡ ÕÕ°¡“„Àâ ∫√‘ ÿ ∑∏‘ Ï π— È π µâ Õß„™â §à “„™â ®à “¬ „π°“√¥”‡π‘ π°“√‡ªì π‡ß‘ πÀ≈“¬æ— π ≈â “π‡À√’ ¬≠ À√— ∞. Õ¬à “ß‰√°Á µ“¡ „π Õ𓧵§“¥«à “À≈— ß®“°∑’Ë ¡’ ¢â Õ∫à ß™’È „π °“√„™â “√‡§¡’ ™’ «¿“æπ’ È °— πÕ¬à “ß°«â “ß ¢«“ß·≈–¡’ °“√º≈‘ µ‡æ‘ Ë ¡¢÷ È π„πª√–‡∑» µà “ßÊ∑—Ë «‚≈° °Á Õ“®¡’ º≈∑”„Àâ √“§“¬“ ≈¥≈߉¥â ·≈–®–°à Õ„Àâ ‡°‘ ¥ª√–‚¬™πå ‰¥â Õ¬à “ß°«â “ߢ«“ß. ªí ®®ÿ ∫— π “√æ‘ … ‚∫∑Ÿ ≈‘ π— ¡ ®÷ ß¡’ ∫∑∫“∑∑’Ë ‚¥¥‡¥à π„π ∑“ß°“√·æ∑¬å ‡æ√“–‡ªì π«‘ ∏’ °“√ √— °…“„À¡à ∑“ߥ⠓πÕ“¬ÿ √°√√¡∑’Ë ¡’ ª√– ‘ ∑∏‘ º≈¥’ ·≈–¡’ ¢â Õ∫à ß™’ È „π°“√π” ¡“„™â „π∑“ß°“√·æ∑¬å ¡“°¢÷È π‡√◊Ë Õ¬Ê µ“¡≈”¥— ∫. ‡Õ° “√Õâ “ßÕ‘ ß Ò. Jankovic J, Hallett M, editors. Thera- py with botulinum toxin. New York: Marcell Dekker Inc; 1994. Ú. American Academy of Neurology. Therapeutics and Technology Assess- ment subcommittee. Assessment : the clinical usefulness of butulinum toxin A in treating neurologic disorders. Neurology 1990; 0: 1332-6. Û. Jankovic J, Brin MF. Therapeutic uses of botulinum toxin. N Engl J Med 1991; 324: 1186-94. Ù. Fahn S, Marsden CD, Calne DB, editors. Dystonia 2: advances in neu- rology. Vol 50. New York: Raven Press; 1981. ı. Savino PJ, Sergott RC, Bosley TM, Schatz NT. Hemifacial spasm treated with botulinum toxin injections. Arch Ophthalmol 1985; 103: 1305-6. ˆ. Jakovic J, Schwartz K. Botulinum toxin treatment of tremors. Neuro- logy 1991; 41: 1185-8. ˜. Clarke CE. Therapeutic potential of botulinum toxin in neurological dis- orders. Quart J Med 1992; 82: 197- 205. ¯. Das TK, Park MD. Botulinum toxin in treating spasticity. Br J Clin Pract 1989; 43: 401-2. ˘. Snow BJ, Tsui JK, Bhatt MH, Varelas M, Hashimoto SA, Caine DM. Treat- ment of spasticity with botulinum toxin: a double-blind study. Ann Neurol 1990; 28: 512-5. Ò. Pasricha PJ, Kalloo AN. Botulinum toxin in treatment of gastrointestinal disorders. In: Jankovic J, Hallett M, editors. Therapy with botulinum toxin. New York: Marcell Dekker Inc; 1994. p. 543-55. ÒÒ. Carruthers A, Carruthers JDA. Botu- linum toxin in treatment of glabeller frown lines and other facial wrinkles. In: Jankovic J. Hallett M, editors. Thera-py with botulinum toxin. New York: Marcell Dekker Inc; 1994. p. 577-95. ÒÚ. Blitzer A, Brin MJ. Laryngeal dys- tonia : a series with botulinim toxin therapy. Ann Otol Rhinol Laryngol 1991; 100: 85-90. ÒÛ. π‘ æπ∏å æ«ß«√‘ π∑√å , Õ¥ÿ ≈¬å «‘ √‘ ¬‡«™°ÿ ≈, ®ÿ Ó≈— °…≥å ‚°¡≈µ√’ . Placebo-con- trolled double-blind cross-over study of botulinum A toxin in hemifacial spasm. Parkin Related Disord 1995; 1: 85-88. ÒÙ. π‘ æπ∏å æ«ß«√‘ π∑√å . Prevalence of dys- tonia and occupational cramps in Thailand. In: Kimura J, Shibasaki H, editors. Recent advances in clini- cal neurophysiology. Amsterdam: Elsevier; 1996. p. 921-32. Òı. π‘ æπ∏å æ«ß«√‘ π∑√å . Pravalence of dys- tonia and occupational cramps in Thailand. In: Excerpta Medica In- ternational Congress Series. 1101. Xth International Congress of EMG and Clinical Neurophysiology, Kyoto, 15- 19 October 1995: S75-76. Òˆ. π‘ æπ∏å æ«ß«√‘ π∑√å , «√æ√√≥ ‡∑æÀ— ¥‘ π, Õ¥ÿ ≈¬å «‘ √‘ ¬‡«™°ÿ ≈. Treatment of various movement disorders with botulinum A toxin injection: an ex- perience of 900 patients. ®æ ∑ ÚıÛ˘; ˜¯: Ú¯Ò-¯. Ò˜. π‘ æπ∏å æ«ß«√‘ π∑√å , «√æ√√≥ ‡∑æÀ— ¥‘ π. An experience of 800 patients with various movement disorders treated with botulinum toxin A injection. J Slovene Med Soc 1996; 65(Suppl III): 89-92. Ò¯. π‘ æπ∏å æ«ß«√‘ π∑√å . An experience of 800 patients with various movement