สำนักราชบัณฑิตยสภา

57 ศศิ ธร ผู้กฤตยาคามี , ปริ มาส หาญบุญคุณูปการ วารสารราชบัณฑิตยสถาน ปีที่ ๓๗ ฉบับที่ ๔ ต.ค.-ธ.ค. ๒๕๕๕ Abstract Rat-bite fever Sasithon Pukrittayakamee Associate Fellow Academy of Science, The Royal Institute, Thailand Borimas Hanboonkunupakarn Department of Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok Rat-bite fever is a rare worldwide systemic bacterial zoonosis. The causative organisms that found in rats are Streptobacillus moniliformis or Spirillum minus. The clinical manifestations are fever, headache, chills, vomiting, rash, and polyarthritis. Diagnosis is mainly based on the history of illness, clinical symptoms, and character- istic growth in cultures. Penicillin is the most effective treatment. If left untreated, the mortality rate is 7 to 10% due to complications. Keywords: rat-bite fever